Clinical and pathomorphological changes in a cat during the course of post-vaccination sarcoma

Prevention of infectious diseases in cats is a guarantee their health. It important to carry out routine annual vaccination maintain stable titer antibodies the cat's blood. However, due injection vaccines into same part body every time, risk such dangerous malignant tumor area as post-vaccination sarcoma increases. This pathology occurs 13–16th vaccinated cat per 10 thousand heads. The article describes clinical case cat. A comprehensive examination sick animal was carried using various diagnostic methods. Clinical and ultrasonographic methods visual diagnosis, hematological studies blood cytological punctate from tumor, well histological neoplasm after surgical removal were used. has been established that looks like diffuse, non-painful, non-hot swelling localized subcutaneous tissue. Ultrasonographically, heterogeneous structure central-type vascularization with infiltrative growth. Hematological indicators are characterized by reactive leukocytosis shift nucleus left an increase sedimentation rate erythrocytes up 15 mm/h. While on 10th day removal, these decrease normal. Cytological showed presence atypical giant multinucleated cells polymorphic nuclei which large number mitoses lymphoid occur. Histological changes represented spindle-shaped strongly expressed atypism pathological forms mitosis cells. stroma permeated vessels, indicates progressive aggressive growth neoplasm.